Factors responsible for the modulation of microbiota and their impact on course of inflammation in inflammatory bowel disease – selected aspects

Authors

  • Natalia Fabisiak Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland
  • Jakub Fichna Zakład Biochemii, Wydział Lekarski, Uniwersytet Medyczny w Łodzi

DOI:

https://doi.org/10.18388/pb.2021_479

Abstract

Inflammatory bowel diseases (IBD) is a group of chronic digestive tract diseases of  characterized by periods of exacerbation and remission. The pathophysiology of IBD is multifactorial and includes microbiological, immunological, genetic and environmental factors. In recent years, the significant role of the intestinal microbiome in the development of these entities has been emphasized. In the article we discussed the impact of selected factors: antimicrobial peptides, vitamin D and iron on the composition of the intestinal microbiota and their role in the immune response and pathogenesis of IBD.

 

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Published

2023-03-27

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Section

Articles