Potential application for stem cells in regenerative medicine and transplantology

Abstract

There are some cells in human body which have an ability to self-renewal and differentiation into particular type of cell. They are classified according to the source of gain and ability to differentiate. Several studies carry on directed stem cells programming toward formation of particular type of cells and also reprogramming somatic stem cells for induced pluripotent stem cells. In the future it could bring hope in elaboration of new ways of disease curing that will give a chance for getting healthy (especially cancers). Stem cells display application in regenerative medicine. They facilitate in repair of damaged or dysfunctional tissues using cells derived from patients. In many cancer types the presence of cancer stem cells was observed. Their ability to self-renewal and unlimited proliferation might be the reason of metastasis and relapse of cancer. The knowledge on complexed signaling pathways and mechanisms of their regulation may be crucial and should lead to elaboration of effective anticancer therapies.