The Balbiani body: morphogenesis and functioning in the oocytes of vertebrates and invertebrates

Abstract

The Balbiani body is an organelle assemblage (termed sometimes a super-organelle) characteristic for the developing oocytes of almost all investigated animal species. In the vast majority of species, this complex resides next to the germinal vesicle and comprises such organelles as mitochondria, elements of endoplasmic reticulum, Golgi complexes as well as accumulations of nuage material. Comparative analyses have shown that the Balbiani bodies, even in closely related organisms, are often morphologically different. The differences concern not only the composition of this assemblage but also mutual relations between its components. So far, it has been found that the Balbiani body is implicated in several cellular processes undergoing in female germline cells. Most importantly this organelle complex is responsible for the delivery and localization of certain macromolecules and organelles to specific regions of the ooplasm (oocyte cytoplasm), as well as in the transfer of mitochondria to the zygote, i.e. to the next generation. Moreover, it has been shown recently that at least in some species the Balbiani body participates in the elimination of nonfunctional, damaged mitochondria from the developing oocytes and egg cells.