The age-related alerations in the enteric nervous system and their impact on peristalsis of the gastrointestinal tract

Authors

  • Agata Szymaszkiewicz Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland
  • Kamil Szymaszkiewicz Department of Pharmacology and Toxicology, Faculty of Medicine, Medical University of Lodz
  • Jakub Fichna Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland
  • Marta Zielińska Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland

DOI:

https://doi.org/10.18388/pb.2021_367

Abstract

Constipation occurs more often in old patients, because the intestinal peristalsis decreases with aging. Constipation is caused due to impaired
motility of the intestines, intestinal barrier damage and the imbalance between the absorption and secretion of water and electrolytes, as well
as disturbed production and release of intestinal hormones, infiltration of the gastrointestinal tract with immune cells, excessive production of
pro-inflammatory cytokines and the alterations in the functions of enteric nervous system.

In this review we will discuss the most important issues associated with the process of aging of the digestive tract, focusing on the enteric nervous system.

Downloads

Download data is not yet available.

Downloads

Published

2021-02-12

Issue

Vol. 67 No. 1 (2021)

Section

Articles

License

Copyright (c) 2021 Advances in Biochemistry

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

All journal contents are distributed under the Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0) license. Everybody may use the content following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made, ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original. There are no additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

Copyright for all published papers © stays with the authors.

Copyright for the journal: © Polish Biochemical Society.