Antiviral compounds isolated from plants

Authors

  • Robert Nawrot Molecular Virology Research Unit, Faculty of Biology, Adam Mickiewicz University, Poznań
  • Alicja Warowicka Department of Animal Physiology and Developmental Biology, Adam Mickiewicz University in Poznań, Poland
  • Oskar Musidlak Molecular Virology Research Unit, Adam Mickiewicz University in Poznań, Poland
  • Martyna Węglewska Molecular Virology Research Unit, Adam Mickiewicz University in Poznań, Poland
  • Sophia Bałdysz Molecular Virology Research Unit, Adam Mickiewicz University in Poznań, Poland
  • Anna Goździcka-Józefiak Molecular Virology Research Unit, Adam Mickiewicz University in Poznań, Poland

DOI:

https://doi.org/10.18388/pb.2020_361

Abstract

Viruses are intracellular pathogens which utilize a number of host metabolic processes for virus replication in addition to proteins which
are encoded for virus itself. Therefore, an effective antiviral drug must interfere with virus encoded proteins without affecting any cellular
metabolic processes. Unfortunately, many antiviral drugs that have an inhibitory effect on virus replication, also have an inhibitory effect on
molecular processes in infected, as well as uninfected, cells. There is currently no approved remedy for many viruses. Plants represent a large
potential source of antiviral agents, such as: alkaloids, flavonoids, phenolic acids, phenylpropanoids, lignins, terpenoids, quinine, tannins, thiophenes, polyacetylenes or proteins. Some of them possess broad spectrum of antiviral activity.

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Published

2021-01-05