Mitochondrial protein import complexes – a phylogenetic perspective

Abstract

The proper functioning of mitochondria and consequently of eukaryotic cells requires protein import into mitochondria. The import proceeds due to the presence of different pathways formed by sophisticated complexes known as the import complexes. The complexes are located in all mitochondrial compartments including the both mitochondrial membranes. Here we collect data concerning the organization of the import complexes and available for representatives of currently distinguished eukaryotic lineages. Despite the lack of many data, the emerging picture indicates at differentiation of the complex organization, particularly observed for the TOM complex. This, in turn, implicates interesting issues for further discussion concerning mitochondria evolution and the knowledge practical application.